![]() Clearance items, however, are considered final sales and cannot be returned. You may have noticed there are only a handful of outlets located in various outlet malls across the country. If you're not fortunate enough to live by one, you can still take advantage of some great deals. Get deals at ĭ: Your first stop is the Dooney & Bourke Web site, which features two sections devoted to lower-priced items. Click on "Under $100" for a great selection of products that won't break the bank. Products available include shoes, jewelry, cosmetic cases, watches, charms, key fobs, umbrellas, wallets and, of course, handbags. ![]() : This website sells only Dooney & Bourke products in original packaging (not used or returned.) Ilovedooney partners with Dooney & Bourke, so you know merchandise is authentic, and sales discounts on this website can reach 60 percent.Ħpm.com: This discount web store offers Dooney & Bourke online deals and lists the manufacturer's suggested retail price (MSRP). The discounts can be substantial, but always shop around and check the deals against other sites for the best value.ĮBay: Ebay has a strong selection of Dooney & Bourke bags. Finding what you want - and making sure it's authentic - can be a tricky feat, but it's less challenging than finding more elite styles such as a genuine Louis Vuitton purse. Keep an eye out for free shipping deals to increase your savings. Many department stores carry Dooney & Bourke products. The bags generally go on sale from time to time, particularly right before a major holiday, so mark your calendar and take advantage of these sales. You can also add to your discount by signing up for a store card (which usually knocks 10 to 15 percent off your purchase) or using an active store coupon (read the fine print so you know if any products are excepted from the discount.)ĭon't be afraid to ask the store manager whether they have a better discount than the one marked on the floor (the sales associates can't make that decision.) Some of the top stores include: Macy's, Dillard's, Nordstrom, and Belk. If you'd rather see the bags in person, visit discount stores like Marshalls and T.J. Both are known to carry Dooney & Bourke handbags at discounted prices. Research has suggested that lycopene may be metabolized by eccentric cleavage, catalyzed by β-carotene oxygenase 2 (BCO2), resulting in the generation of apo-lycopenals.Again, the selection will not be as vast as it would be at an outlet, but you can expect to find a handful of styles. We now show that several other apo-lycopenals are also present in raw and processed foods, as well as in human plasma.Īpo-6′-lycopenal and apo-8′-lycopenal have been reported previously in raw tomato. Apo-lycopenal standards were prepared by in vitro oxidation of lycopene, and a high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method using atmospheric pressure chemical ionization in negative mode was developed to separate and detect the apo-6′-, 8′-, 10′-, 12′-, 14′-, and 15′-lycopenal products formed in the reaction. Hexane/acetone extracts of raw tomato, red grapefruit, watermelon, and processed tomato products were analyzed, as well as plasma of individuals who had consumed tomato juice for eight weeks. Apo-6′-, 8′-, 10′-, 12′-, and 14′-lycopenals were detected and quantified in all food products tested, as well as plasma. The sum of apo-lycopenals was 6.5 µg/100 g ‘Roma’ tomato, 73.4 µg/100 g tomato paste, and 1.9 nmol/L of plasma. We conclude that several apo-lycopenals, in addition to apo-6′- and 8′-lycopenal, are present in lycopene containing foods. In addition, the presence of apo-lycopenals in plasma may derive from the absorption of apo-lycopenals directly from food and/or human metabolism.Įpidemiological studies have repeatedly correlated increased consumption of tomato and tomato products with reduction in the incidence of a number of cancers and other chronic diseases ( 1– 5). Many researchers have suggested that lycopene, the most abundant carotenoid in red tomatoes, may be responsible for this effect ( 6– 8). ![]() It has also been suggested that metabolites of lycopene may be bioactive ( 9, 10). ( 11) first reported lycopene derivatives in human blood plasma, which were later identified as two diastereomeric forms of 2,6-cyclolycopene-1,5-diol ( 12).
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |